Deutch works with Water. org for their Give. Water. org campaign.  She supports Planned Parenthood and was part of its rally with pro-choice advocates and leaders celebrating the 45th anniversary of Roe v. Wade at Sacramento, California.  She has performed for the benefit of Alzheimer's Association and "What a pair!" Org with her mother Lea Thompson and sister Madelyn Deutch. With her family, she has worked for more than a decade with Corazón de Vida, which supports orphanages in Baja, Mexico.  She participated in the 2017 Women's March and 2018.  She is also a part of the Embrace Ambition campaign of the Tory Burch Foundation.  She was one of the celebrity ambassadors for 7th annual "Shop for Success" charity designer shopping event that supports the efforts of Dress For Success.  She has also shown her support towards anti-sexual harassment movement Time's Up.  She has been a part of several fundraising campaigns for charity and in support of various causes.